Description

2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinonitrile is a high-value, fluorinated heterocyclic building block of significant interest in modern organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure can impart desirable biological and physicochemical properties. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands and functionalized heterocycles used in catalysis and advanced polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorination chemistry and heterocycle construction.

Basic Information

Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinonitrile
CAS No.	1228665-87-9
Molecular Formula	C10H10FN3
Molecular Weight	191.21 g/mol
Synonyms	2-Fluoro-6-(1-pyrrolidinyl)-3-pyridinecarbonitrile; 6-(Pyrrolidin-1-yl)-2-fluoronicotinonitrile; 3-Cyano-2-fluoro-6-(pyrrolidin-1-yl)pyridine; 2-Fluoro-6-pyrrolidin-1-ylpyridine-3-carbonitrile; 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile; Nicotinonitrile, 2-fluoro-6-(1-pyrrolidinyl)-; 1228665-87-9
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Pyrrolidin-1-Yl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.