Description

1-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanol is a high-value fluorinated pyridine derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its core value lies in the unique combination of the pyridine heterocycle and the trifluoromethyl group, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating fluorinated organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	1-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanol
CAS No.	1228631-54-6
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	3-Pyridineethanol, 6-(trifluoromethyl)-; 1-[6-(Trifluoromethyl)-3-pyridinyl]ethanol; 1-(6-(Trifluoromethyl)pyridin-3-yl)ethan-1-ol; (6-(Trifluoromethyl)pyridin-3-yl)methanol (related); α-(6-(Trifluoromethyl)-3-pyridyl)ethanol; 5-(1-Hydroxyethyl)-2-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.