Description

2-(4-Iodophenoxy)-6-(Trifluoromethyl)Pyridine is a high-purity, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a phenoxy-iodo moiety with a trifluoromethylpyridine core, which is critical for modulating the physicochemical properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in creating advanced herbicides, fungicides, and insecticides where the iodine and trifluoromethyl groups enhance bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for creating specialty polymers with tailored electronic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for imaging and diagnostic applications due to its iodine handle for further functionalization.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.

Basic Information

Product Name	2-(4-Iodophenoxy)-6-(Trifluoromethyl)Pyridine
CAS No.	1227955-16-9
Molecular Formula	C12H7F3INO
Molecular Weight	365.09 g/mol
Synonyms	2-(4-Iodophenoxy)-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-(4-iodophenoxy)pyridine; 2-(p-Iodophenoxy)-6-(trifluoromethyl)pyridine; 4-(6-(Trifluoromethyl)pyridin-2-yloxy)iodobenzene; Pyridine, 2-(4-iodophenoxy)-6-(trifluoromethyl)-; 1227955-16-9
EINECS	Contact for details

Quality Control

Our 2-(4-Iodophenoxy)-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures a reliable supply of this high-value intermediate for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.