Description

Gsk 2334470 is a potent and selective small molecule inhibitor primarily used in biochemical and pharmacological research. This compound, identified by CAS No. 1227911-45-6, is a valuable tool for studying specific intracellular signaling pathways and enzyme functions. It is essential for researchers and scientists in the fields of oncology, immunology, and molecular biology who require high-purity chemical probes for target validation and drug discovery efforts.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic assays to study kinase activity and signal transduction mechanisms.
• Pharmacological Studies: Employed in cell-based assays to investigate the effects of pathway inhibition on cell proliferation, apoptosis, and differentiation.
• Drug Discovery & Target Validation: Serves as a critical reference compound and chemical probe for validating novel therapeutic targets in early-stage R&D.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in cancer biology, neuroscience, and metabolic diseases.
• Preclinical Development: Acts as a lead compound or comparator in animal model studies to evaluate efficacy and mechanism of action.

Basic Information

Product Name	Gsk 2334470
CAS No.	1227911-45-6
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.41 g/mol
Synonyms	GSK2334470; GSK-2334470; 4-(4-(3-(Pyridin-4-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrimidin-2-yl)morpholine; AZD-2014 analog; mTOR inhibitor; 1H-Pyrazolo[3,4-b]pyridine, 4-[4-[3-(4-pyridinyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-2-pyrimidinyl]morpholine
EINECS	Contact for details

Quality Control

Our Gsk 2334470 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/LC-MS for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (Mass)	Conforms (M+H+: 377.2)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.