Description

2-Bromomethyl-4-Trifluoromethyl-Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a stable trifluoromethyl moiety, makes it indispensable for introducing functional complexity into target molecules. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyridine-based ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise functionalization.

Basic Information

Product Name	2-Bromomethyl-4-Trifluoromethyl-Pyridine
CAS No.	1227606-71-4
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	4-(Trifluoromethyl)-2-(bromomethyl)pyridine; 2-(Bromomethyl)-4-(trifluoromethyl)pyridine; Pyridine, 2-(bromomethyl)-4-(trifluoromethyl)-; 2-Bromo-4-trifluoromethyl-pyridine; 2-Bromomethyl-4-trifluoromethylpyridine; 4-Trifluoromethyl-2-bromomethylpyridine; α-Bromo-4-trifluoromethyl-2-picoline
EINECS	Contact for details

Quality Control

Our 2-Bromomethyl-4-Trifluoromethyl-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in GMP-intermediate and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.