Description

4,5-Dimethyl-2-Fluoropyridine is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methyl groups, which significantly influences the electronic and steric properties of target molecules, enabling fine-tuning of biological activity and material characteristics. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require specific fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes due to the modifiable pyridine core.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Item	Detail
Product Name	4,5-Dimethyl-2-Fluoropyridine
CAS No.	1227602-71-2
Molecular Formula	C7H8FN
Molecular Weight	125.15 g/mol
Synonyms	2-Fluoro-4,5-dimethylpyridine; 4,5-Dimethyl-2-fluoropyridine; 2-Fluoro-4,5-lutidine; 4,5-Dimethylpyridine, 2-fluoro-; Fluoropyridine derivative CAS 1227602-71-2
EINECS	Contact for details

Quality Control

Our 4,5-Dimethyl-2-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under GMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.