Description

3-Fluoro-6-Oxo-1,6-Dihydropyridine-2-Carbaldehyde is a high-purity fluorinated pyridone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both a reactive aldehyde group and a fluorinated heterocyclic core, makes it indispensable for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create labeled compounds or covalent inhibitors for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	3-Fluoro-6-Oxo-1,6-Dihydropyridine-2-Carbaldehyde
CAS No.	1227602-39-2
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	2-Formyl-3-fluoro-6-hydroxypyridine; 3-Fluoro-2-formyl-6-hydroxypyridine; 3-Fluoro-6-hydroxy-2-pyridinecarboxaldehyde; 3-Fluoro-6-hydroxypicolinaldehyde; 6-Hydroxy-3-fluoropicolinaldehyde; 2-Pyridinecarboxaldehyde, 3-fluoro-6-hydroxy-; 1,6-Dihydro-3-fluoro-6-oxo-2-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-6-Oxo-1,6-Dihydropyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP (current Good Manufacturing Practice) requirements for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and may be hygroscopic; therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.