Description

2,3-Difluoropyridin-4-Amine CAS NO 1227602-34-7 is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring both fluorine atoms and an amine group on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for functionalized ligands in catalysis and for creating specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical spaces in heterocyclic and fluorine chemistry.
• Liquid Crystal & Electronic Material Synthesis: A potential intermediate for creating fluorinated components used in display technologies and organic semiconductors.

Basic Information

Product Name	2,3-Difluoropyridin-4-Amine
CAS No.	1227602-34-7
Molecular Formula	C5H4F2N2
Molecular Weight	130.10 g/mol
Synonyms	4-Amino-2,3-difluoropyridine; 2,3-Difluoro-4-pyridinamine; 2,3-Difluoropyridin-4-ylamine; 4-Pyridinamine, 2,3-difluoro-; 2,3-Difluoro-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 2,3-Difluoropyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.