Description

(3-Fluoro-6-Trifluoromethyl-Pyridin-2-Yl)-Methanol is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and trifluoromethyl groups, makes it an essential intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorinated pyridine moiety enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(3-Fluoro-6-Trifluoromethyl-Pyridin-2-Yl)-Methanol
CAS No.	1227601-29-7
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	2-(Hydroxymethyl)-3-fluoro-6-(trifluoromethyl)pyridine; (3-Fluoro-6-(trifluoromethyl)pyridin-2-yl)methanol; 3-Fluoro-6-trifluoromethyl-2-pyridinemethanol; 2-Pyridinemethanol, 3-fluoro-6-(trifluoromethyl)-; 3-Fluoro-6-trifluoromethyl-pyridine-2-yl-methanol
EINECS	Contact for details

Quality Control

Every batch of (3-Fluoro-6-Trifluoromethyl-Pyridin-2-Yl)-Methanol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (NMR, IR), and impurity profile, is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.