Description

[6-(4-Fluoro-Phenyl)-Pyridin-3-Yl]-Acetonitrile is a high-value, fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a nitrile and a fluorinated aromatic system, makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes and diagnostics.

Basic Information

Product Name	[6-(4-Fluoro-Phenyl)-Pyridin-3-Yl]-Acetonitrile
CAS No.	1227599-81-6
Molecular Formula	C₁₃H₉FN₂
Molecular Weight	212.22 g/mol
Synonyms	2-[6-(4-Fluorophenyl)pyridin-3-yl]acetonitrile; (6-(4-Fluorophenyl)pyridin-3-yl)acetonitrile; 2-(6-(4-Fluorophenyl)-3-pyridinyl)acetonitrile; 6-(4-Fluorophenyl)-3-pyridineacetonitrile; 3-Pyridineacetonitrile, 6-(4-fluorophenyl)-; 1227599-81-6; 6-(4-Fluorophenyl)nicotinonitrile derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. We provide material that typically meets a purity specification of ≥95% (by HPLC), with higher grades available. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.