Description

(2,4-Difluoropyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a functionalized, difluorinated aromatic scaffold that enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, particularly where the introduction of fluorine atoms is required to modulate biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, especially in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental stability.
• Material Science Research: Used in the synthesis of specialty chemicals, ligands for catalysis, and advanced organic materials.
• Fluorine Chemistry Studies: A valuable substrate for exploring new fluorination reactions and studying structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	(2,4-Difluoropyridin-3-Yl)Methanol
CAS No.	1227598-92-6
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	3-(Hydroxymethyl)-2,4-difluoropyridine; 2,4-Difluoropyridine-3-methanol; 2,4-Difluoro-3-pyridinemethanol; (2,4-Difluoro-3-pyridinyl)methanol; 3-Pyridinemethanol, 2,4-difluoro-; (2,4-Difluoropyridin-3-yl)methanol
EINECS	Contact for details

Quality Control

Our (2,4-Difluoropyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.