Description

3-(Trifluoromethyl)Pyridine-4-Methanol CAS NO 1227598-69-7 is a high-value fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a hydroxymethyl substituent on the pyridine ring, makes it an essential intermediate for creating molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing drugs targeting the central nervous system, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group often improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for asymmetric synthesis.
• Material Science Research: Employed in the development of functional materials, such as liquid crystals, organic semiconductors, and advanced polymers.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways due to its ability to mimic natural substrates.

Basic Information

Product Name	3-(Trifluoromethyl)Pyridine-4-Methanol
CAS No.	1227598-69-7
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	4-(Hydroxymethyl)-3-(trifluoromethyl)pyridine; (3-Trifluoromethyl-4-pyridyl)methanol; 3-Trifluoromethyl-4-pyridinemethanol; 4-Pyridinemethanol, 3-(trifluoromethyl)-; α-(3-Trifluoromethyl-4-pyridyl)methanol
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyridine-4-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.