Description

(3,6-Difluoropyridin-2-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a hydroxymethyl group and fluorine atoms at strategic positions, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the difluoropyridine moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials for electronic or optical applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	(3,6-Difluoropyridin-2-Yl)Methanol
CAS No.	1227598-08-4
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2-(Hydroxymethyl)-3,6-difluoropyridine; 3,6-Difluoro-2-pyridinemethanol; (3,6-Difluoropyridin-2-yl)methanol; 3,6-Difluoropyridine-2-methanol; (3,6-Difluoro-2-pyridinyl)methanol; 2-Pyridinemethanol, 3,6-difluoro-; 3,6-Difluoro-2-(hydroxymethyl)pyridine
EINECS	Contact for details

Quality Control

Our (3,6-Difluoropyridin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.