Description

2-Fluoro-5-Methoxynicotinaldehyde is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both aldehyde and methoxy substituents on a fluorinated pyridine core, makes it an essential intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for synthesizing organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probes: Utilized in the design of fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development.

Basic Information

Product Name	2-Fluoro-5-Methoxynicotinaldehyde
CAS No.	1227597-35-4
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Methoxy-2-fluoropyridine-3-carbaldehyde; 3-Formyl-5-methoxy-2-fluoropyridine; 2-Fluoro-5-methoxypyridine-3-carboxaldehyde; 2-Fluoro-5-methoxy-3-pyridinecarboxaldehyde; Nicotinaldehyde, 2-fluoro-5-methoxy-; 1227597-35-4
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methoxynicotinaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.