Description

3-Fluoro-4-Iodo-2-Methoxypyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and iodine atoms for bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient pyridine core.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes, where the iodine atom allows for further functionalization via cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific custom synthesis projects requiring complex halogenated heterocycles.

Basic Information

Product Name	3-Fluoro-4-Iodo-2-Methoxypyridine
CAS No.	1227595-09-6
Molecular Formula	C6H5FINO
Molecular Weight	253.01 g/mol
Synonyms	2-Methoxy-3-fluoro-4-iodopyridine; 4-Iodo-3-fluoro-2-methoxypyridine; 3-Fluoro-4-iodo-2-pyridinol methyl ether; 3-Fluoro-4-iodo-2-methoxy-pyridine; 1227595-09-6
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Iodo-2-Methoxypyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment, supporting compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.