Description

2-Hydroxy-3-Fluoro-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional fluorinated pyridine derivative. This compound is a critical advanced intermediate for synthesizing complex molecules, prized for its ability to introduce both fluorine and a trifluoromethyl group, which are key motifs for modulating the physicochemical properties of target compounds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and functional polymers that require specific fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in the design of chemical probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Hydroxy-3-Fluoro-4-(Trifluoromethyl)Pyridine
CAS No.	1227594-89-9
Molecular Formula	C7H3F4NO
Molecular Weight	193.10 g/mol
Synonyms	3-Fluoro-4-(trifluoromethyl)pyridin-2-ol; 2-Pyridinol, 3-fluoro-4-(trifluoromethyl)-; 3-Fluoro-4-trifluoromethyl-2-hydroxypyridine; 2-Hydroxy-3-fluoro-4-trifluoromethylpyridine; 4-(Trifluoromethyl)-3-fluoropyridin-2-ol; FC-1133 (Potential research code); 3-Fluoro-4-(trifluoromethyl)-2(1H)-pyridinone (Tautomeric form)
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Fluoro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. We provide material that typically meets high-purity standards suitable for research and advanced synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.