Description

2-Fluoro-5-Methoxypyridin-3-Ol is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A high-purity starting material for custom synthesis projects and scale-up processes under GMP or ISO standards.

Basic Information

Product Name	2-Fluoro-5-Methoxypyridin-3-Ol
CAS No.	1227593-83-0
Molecular Formula	C6H6FNO2
Molecular Weight	143.12 g/mol
Synonyms	3-Hydroxy-2-fluoro-5-methoxypyridine; 2-Fluoro-5-methoxy-3-pyridinol; 5-Methoxy-2-fluoropyridin-3-ol; 2-Fluoro-5-methoxypyridin-3-ol; 3-Pyridinol, 2-fluoro-5-methoxy-; 1227593-83-0
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxypyridin-3-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems support development under cGMP and ISO 9001 standards for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.