Description

3-Fluoro-2-Methoxy-Pyridine-4-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular architecture, featuring both fluorine and aldehyde functional groups on a methoxy-pyridine scaffold, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-deficient pyridine core.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Fluoro-2-Methoxy-Pyridine-4-Carbaldehyde
CAS No.	1227589-00-5
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	4-Formyl-3-fluoro-2-methoxypyridine; 3-Fluoro-2-methoxyisonicotinaldehyde; 2-Methoxy-3-fluoropyridine-4-carboxaldehyde; 3-Fluoro-2-methoxypyridine-4-carbaldehyde; 1227589-00-5; 4-Pyridinecarboxaldehyde, 3-fluoro-2-methoxy-; 3-Fluoro-2-methoxy-4-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Methoxy-Pyridine-4-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee supply chain transparency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being light-sensitive and easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.