Description

6-Bromo-5-Fluoronicotinaldehyde is a high-value fluorinated and brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it indispensable for introducing specific functional groups and modifying molecular scaffolds with precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in medicinal chemistry, particularly in the synthesis of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical research to study protein-ligand interactions.
• Custom Synthesis & Scale-Up: An essential starting material for contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	6-Bromo-5-Fluoronicotinaldehyde
CAS No.	1227588-59-1
Molecular Formula	C7H3BrFNO
Molecular Weight	203.99 g/mol
Synonyms	5-Fluoro-6-bromonicotinaldehyde; 6-Bromo-5-fluoropyridine-3-carboxaldehyde; 3-Bromo-2-fluoropyridine-5-carbaldehyde; 5-Fluoro-6-bromopyridine-3-carbaldehyde; 2-Fluoro-3-bromopyridine-5-carboxaldehyde; 6-Bromo-5-fluoro-3-pyridinecarboxaldehyde; 6-Bromo-5-fluoronicotinaldehyde; 1227588-59-1
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 6-Bromo-5-Fluoronicotinaldehyde is analyzed using advanced techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. Our quality system supports development from milligram to kilogram scale with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.