Description

5-Bromo-6-Fluoropyridine-2-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the bromo and fluoro substituents contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the construction of organic semiconductors, liquid crystals, and photoactive materials due to its electron-deficient pyridine core and functional aldehyde group.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes, leveraging its reactive aldehyde for bioconjugation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Product Name	5-Bromo-6-Fluoropyridine-2-Carbaldehyde
CAS No.	1227583-93-8
Molecular Formula	C6H3BrFNO
Molecular Weight	204.00 g/mol
Synonyms	2-Bromo-3-fluoropyridine-6-carbaldehyde; 6-Fluoro-5-bromopyridine-2-carboxaldehyde; 2-Formyl-5-bromo-6-fluoropyridine; 5-Bromo-6-fluoro-2-pyridinecarboxaldehyde; 5-Bromo-6-fluoro-2-formylpyridine; 2-Pyridinecarboxaldehyde, 5-bromo-6-fluoro-; 1227583-93-8
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-6-Fluoropyridine-2-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.