Description

2-Fluoro-5-Phenylnicotinaldehyde is a high-value fluorinated nicotinaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and an aldehyde group on the pyridine ring, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Building block for creating specialized ligands, catalysts, and organic electronic materials.
• Chemical Synthesis: Versatile aldehyde functionality for condensation reactions, such as the synthesis of imines, hydrazones, and other heterocyclic compounds.
• Academic & Contract Research: Essential reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	2-Fluoro-5-Phenylnicotinaldehyde
CAS No.	1227582-82-2
Molecular Formula	C₁₂H₈FNO
Molecular Weight	201.20 g/mol
Synonyms	5-Phenyl-2-fluoronicotinaldehyde; 2-Fluoro-5-phenyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 2-fluoro-5-phenyl-; 2-Fluoro-5-phenylpyridine-3-carbaldehyde; 1227582-82-2; 2-Fluoro-5-phenyl-3-formylpyridine; 5-Phenyl-2-fluoropyridine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Phenylnicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.