Description

2-Methoxy-6-(Trifluoromethyl)Isonicotinic Acid is a high-value, multi-functional chemical intermediate characterized by its unique trifluoromethyl and methoxy-substituted pyridine core. This compound matters for its role in imparting desirable properties like metabolic stability and enhanced lipophilicity to target molecules, making it a critical building block in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals due to its distinct electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	2-Methoxy-6-(Trifluoromethyl)Isonicotinic Acid
CAS No.	1227581-20-5
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	6-(Trifluoromethyl)-2-methoxypyridine-4-carboxylic Acid; 2-Methoxy-6-(trifluoromethyl)pyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2-methoxy-6-(trifluoromethyl)-; Isonicotinic acid, 2-methoxy-6-(trifluoromethyl)-; 2-Methoxy-6-trifluoromethylisonicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-6-(Trifluoromethyl)Isonicotinic Acid is produced under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.