Description

3-Hydroxy-2-Methoxy-5-(Trifluoromethyl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a pyridine scaffold with methoxy, hydroxy, and trifluoromethyl substituents, enabling precise molecular modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex chelating ligands used in homogeneous catalysis and material science.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Hydroxy-2-Methoxy-5-(Trifluoromethyl)Pyridine
CAS No.	1227580-74-6
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	5-(Trifluoromethyl)-2-methoxypyridin-3-ol; 2-Methoxy-5-(trifluoromethyl)pyridin-3-ol; 3-Hydroxy-2-methoxy-5-trifluoromethylpyridine; 3-Pyridinol, 2-methoxy-5-(trifluoromethyl)-; 2-Methoxy-3-hydroxy-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Methoxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.