Description

2-Fluoro-4-Iodo-3-Methoxypyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen and methoxy functionalities into heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science: Serves as a building block for creating functional organic materials, such as liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing diverse heterocyclic libraries in academic and industrial R&D settings.
• Ligand Synthesis: Potential precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-4-Iodo-3-Methoxypyridine
CAS No.	1227580-53-1
Molecular Formula	C6H5FINO
Molecular Weight	253.01 g/mol
Synonyms	3-Methoxy-2-fluoro-4-iodopyridine; 4-Iodo-2-fluoro-3-methoxypyridine; 2-Fluoro-3-methoxy-4-iodopyridine; Pyridine, 2-fluoro-4-iodo-3-methoxy-; FIMP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 2-Fluoro-4-Iodo-3-Methoxypyridine is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. We adhere to strict in-house specifications designed for research and commercial synthesis. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.