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2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Methanol CAS NO 1227580-29-1


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CAS No.:1227580-29-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorinated pyridine core contributes to efficacy and environmental profile.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and molecular recognition studies.
  • Material Science Research: Employed in the synthesis of fluorinated organic electronic materials and liquid crystals.
  • Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name 2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Methanol
CAS No. 1227580-29-1
Molecular Formula C7H5F4NO
Molecular Weight 195.12 g/mol
Synonyms (6-(Trifluoromethyl)-2-fluoropyridin-3-yl)methanol; 3-Pyridinemethanol, 2-fluoro-6-(trifluoromethyl)-; 2-Fluoro-6-trifluoromethyl-3-pyridinemethanol; 2-Fluoro-6-(trifluoromethyl)-3-pyridylmethanol; 2-Fluoro-6-(trifluoromethyl)nicotinyl alcohol
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Quality Control

Our 2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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