Description

2-Fluoro-3-Iodo-5-Methoxypyridine is a halogenated pyridine derivative serving as a versatile and high-value synthetic building block. Its molecular structure, featuring fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for applications such as medicinal chemistry, process development, and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create biaryl structures.
• Chemical Biology Probes: Serves as a precursor for synthesizing molecular probes and tags used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-3-Iodo-5-Methoxypyridine
CAS No.	1227579-57-8
Molecular Formula	C6H5FINO
Molecular Weight	253.01 g/mol
Synonyms	5-Methoxy-2-fluoro-3-iodopyridine; 3-Iodo-2-fluoro-5-methoxypyridine; 2-Fluoro-3-iodo-5-methoxy-pyridine; Pyridine, 2-fluoro-3-iodo-5-methoxy-; FIMP (common abbreviation)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-5-Methoxypyridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality commitment ensures reliable supply for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.