Description

2,3-Difluoro-4-methoxypyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or with fluorinated bioactive components.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its electron-deficient pyridine core and methoxy functionality.
• Chemical Biology Probes: Utilized as a building block for fluorinated probes and tags in medicinal chemistry and diagnostic assay development.

Basic Information

Product Name	2,3-Difluoro-4-methoxypyridine
CAS No.	1227578-88-2
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	4-Methoxy-2,3-difluoropyridine; 2,3-Difluoro-4-methoxypyridine; 2,3-Difluoro-4-pyridinol methyl ether; 4-Pyridinol, 2,3-difluoro-, methyl ether
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.