Description

6-Fluoro-3-Hydroxy-2-Methylpyridine is a high-purity fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which introduces both fluorine and hydroxyl functional groups onto the pyridine core, enabling precise molecular modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Fluoro-3-Hydroxy-2-Methylpyridine
CAS No.	1227577-28-7
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	2-Methyl-6-fluoro-3-pyridinol; 3-Hydroxy-2-methyl-6-fluoropyridine; 6-Fluoro-2-methyl-3-pyridinol; 6-Fluoro-3-hydroxy-2-picoline; 2-Methyl-6-fluoro-3-hydroxypyridine; 6-Fluoro-3-pyridinol, 2-methyl-; 3-Pyridinol, 6-fluoro-2-methyl-
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-Hydroxy-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.