Description

Methyl 2-Fluoro-5-Methylpyridine-3-Carboxylate is a high-purity fluorinated pyridine derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and specific heterocyclic motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluoropyridine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions and building block methodologies.
• Fluorine Chemistry: A valuable substrate for further fluorination and functionalization reactions due to its reactive ester and fluorine groups.

Basic Information

Product Name	Methyl 2-Fluoro-5-Methylpyridine-3-Carboxylate
CAS No.	1227575-36-1
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Methyl 2-Fluoro-5-methylnicotinate; 3-Pyridinecarboxylic acid, 2-fluoro-5-methyl-, methyl ester; 2-Fluoro-5-methylnicotinic acid methyl ester; Methyl 2-fluoro-5-methyl-3-pyridinecarboxylate; 2-Fluoro-5-methyl-pyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Fluoro-5-Methylpyridine-3-Carboxylate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.