Description

(5-Fluoropyrimidin-2-Yl)Methanol CAS NO 1227574-72-2 is a high-value fluorinated pyrimidine derivative, a crucial building block in modern organic synthesis. Its primary commercial value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists and process engineers working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral, anticancer, and anti-inflammatory drug candidates, leveraging the bioisosteric properties of the fluorine atom.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluoropyrimidine core enhances biological activity and stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes, enzyme inhibitors, and other tools for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	(5-Fluoropyrimidin-2-Yl)Methanol
CAS No.	1227574-72-2
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	2-(Hydroxymethyl)-5-fluoropyrimidine; 5-Fluoro-2-pyrimidinemethanol; (5-Fluoro-2-pyrimidinyl)methanol; 5-Fluoropyrimidine-2-methanol; 2-Pyrimidinemethanol, 5-fluoro-; 5-Fluoro-2-(hydroxymethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our (5-Fluoropyrimidin-2-Yl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can support documentation for use in cGMP (Current Good Manufacturing Practice) environments and compliance with REACH, TSCA, and other global chemical inventories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.