Description

2,4-Difluoro-Pyridine-3-Carbaldehyde is a high-purity fluorinated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and an aldehyde functional group, which enable precise molecular modifications for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the difluoropyridine core enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom chemical synthesis services targeting complex, fluorinated target molecules.

Basic Information

Product Name	2,4-Difluoro-Pyridine-3-Carbaldehyde
CAS No.	1227564-60-4
Molecular Formula	C6H3F2NO
Molecular Weight	143.09 g/mol
Synonyms	3-Formyl-2,4-difluoropyridine; 2,4-Difluoropyridine-3-carboxaldehyde; 2,4-Difluoro-3-pyridinecarboxaldehyde; 2,4-Difluoro-3-formylpyridine; 3-Pyridinecarboxaldehyde, 2,4-difluoro-; 1227564-60-4; 2,4-Difluoronicotinaldehyde
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.