Description

(6-Bromo-2-Fluoropyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both bromo and fluoro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form biaryl structures.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes, tags, and linkers for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	(6-Bromo-2-Fluoropyridin-3-Yl)Methanol
CAS No.	1227563-78-1
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	3-(Hydroxymethyl)-6-bromo-2-fluoropyridine; (6-Bromo-2-fluoro-3-pyridinyl)methanol; 6-Bromo-2-fluoro-3-pyridinemethanol; 2-Fluoro-6-bromo-3-pyridinemethanol; 6-Bromo-2-fluoropyridine-3-methanol; 3-Pyridinemethanol, 6-bromo-2-fluoro-
EINECS	Contact for details

Quality Control

Our (6-Bromo-2-Fluoropyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.