Description

2-Chloro-3-Methoxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and trifluoromethylated pyridine core. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of modern pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Used in the synthesis of advanced organic materials, including liquid crystals, organic semiconductors, and functional polymers.
• Chemical Biology & Proteomics: Employed as a versatile building block for creating molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-Chloro-3-Methoxy-5-(Trifluoromethyl)Pyridine
CAS No.	1227563-67-8
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	2-Chloro-3-methoxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-chloro-3-methoxypyridine; 3-Methoxy-2-chloro-5-trifluoromethylpyridine; Pyridine, 2-chloro-3-methoxy-5-(trifluoromethyl)-; 1227563-67-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methoxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.