Description

4-Pyridinecarboxylic Acid, 2-Fluoro-5-Methyl-, Methyl Ester is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which introduces both fluorine and ester functionalities to the pyridine core, enabling precise modifications in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals, where fluorinated heterocycles are valued for their electronic properties.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds and molecular probes for studying biological mechanisms and enzyme functions.

Basic Information

Product Name	4-Pyridinecarboxylic Acid, 2-Fluoro-5-Methyl-, Methyl Ester
CAS No.	1227516-39-3
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Methyl 2-Fluoro-5-methylisonicotinate; 2-Fluoro-5-methylisonicotinic Acid Methyl Ester; 2-Fluoro-5-methylpyridine-4-carboxylic Acid Methyl Ester; 4-Carbomethoxy-2-fluoro-5-methylpyridine; Isonicotinic Acid, 2-Fluoro-5-Methyl-, Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 4-Pyridinecarboxylic Acid, 2-Fluoro-5-Methyl-, Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.