Description

[3-Fluoro-5-(Trifluoromethyl)Pyridin-2-Yl]Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, is essential for modulating the physicochemical properties of target molecules, particularly enhancing metabolic stability and lipophilicity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorinated pyridine moiety contributes to efficacy and environmental profile.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its ability to fine-tune electronic properties.
• Material Science Research: Acts as a precursor for functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	[3-Fluoro-5-(Trifluoromethyl)Pyridin-2-Yl]Methanol
CAS No.	1227515-52-7
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	(3-Fluoro-5-(trifluoromethyl)pyridin-2-yl)methanol; 2-Pyridinemethanol, 3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-5-trifluoromethyl-2-pyridinemethanol; (3-Fluoro-5-(trifluoromethyl)-2-pyridinyl)methanol; 2-(Hydroxymethyl)-3-fluoro-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our [3-Fluoro-5-(Trifluoromethyl)Pyridin-2-Yl]Methanol is manufactured under strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.