Description

3-Fluoro-5-Hydroxypyridine-2-Carbaldehyde is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is prized for its unique molecular architecture, featuring both an aldehyde and a hydroxyl group on a fluorinated pyridine ring, enabling precise derivatization. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of organic electronic materials and metal-organic frameworks (MOFs) due to its functional group diversity.
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and the development of biochemical tools.

Basic Information

Product Name	3-Fluoro-5-Hydroxypyridine-2-Carbaldehyde
CAS No.	1227515-00-5
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	2-Formyl-3-fluoro-5-hydroxypyridine; 3-Fluoro-5-hydroxy-2-pyridinecarboxaldehyde; 5-Hydroxy-3-fluoropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 3-fluoro-5-hydroxy-; 3-Fluoro-5-hydroxypicolinaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Hydroxypyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.