Description

4-Fluoro-6-Methylpyridin-2-Ol CAS NO 1227508-66-8 is a high-value fluorinated pyridine derivative, a crucial building block in modern organic synthesis. Its unique structure, featuring both fluorine and a hydroxyl group on the pyridine ring, makes it an essential intermediate for developing advanced pharmaceuticals and agrochemicals. This compound is primarily sought after by research institutions and industrial manufacturers in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated probes for studying enzyme mechanisms and protein interactions.

Basic Information

Item	Detail
Product Name	4-Fluoro-6-Methylpyridin-2-Ol
CAS No.	1227508-66-8
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	2-Hydroxy-4-fluoro-6-methylpyridine; 4-Fluoro-6-methyl-2-pyridinol; 4-Fluoro-6-methyl-2(1H)-pyridinone; 6-Methyl-4-fluoropyridin-2-ol; 4-Fluoro-6-methyl-2-hydroxypyridine; 2-Pyridinol, 4-fluoro-6-methyl-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-6-Methylpyridin-2-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.