Description

2-Chloromethyl-3-Fluoro-5-Trifluoromethyl-Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its molecular structure, featuring reactive chloromethyl and electron-withdrawing fluorine/trifluoromethyl groups, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials and liquid crystals due to its fluorinated aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis organizations serving the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Chloromethyl-3-Fluoro-5-Trifluoromethyl-Pyridine
CAS No.	1227507-89-2
Molecular Formula	C8H4ClF4N
Molecular Weight	225.57 g/mol
Synonyms	3-Fluoro-5-(trifluoromethyl)-2-pyridinemethanol chloride; 2-(Chloromethyl)-3-fluoro-5-(trifluoromethyl)pyridine; 3-Fluoro-5-trifluoromethyl-2-chloromethylpyridine; 2-Pyridinemethanol, 3-fluoro-5-(trifluoromethyl)-, chloride; 2-Chloromethyl-3-fluoro-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloromethyl-3-Fluoro-5-Trifluoromethyl-Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we are compliant with relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.