Description

[2-Chloro-4-(Trifluoromethyl)Pyridin-3-Yl]Methanol is a high-value pyridine derivative and a versatile chemical building block. Its molecular structure, featuring both a chlorinated and a trifluoromethylated pyridine ring, makes it a critical intermediate for the synthesis of advanced agrochemicals and pharmaceuticals. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a core building block for next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Ligand and Catalyst Preparation: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions in complex molecule synthesis.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	[2-Chloro-4-(Trifluoromethyl)Pyridin-3-Yl]Methanol
CAS No.	1227502-97-7
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	(2-Chloro-4-(trifluoromethyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 2-chloro-4-(trifluoromethyl)-; 2-Chloro-4-trifluoromethyl-3-pyridinemethanol; 2-Chloro-4-(trifluoromethyl)-3-hydroxymethylpyridine; 2-Chloro-4-(trifluoromethyl)pyridine-3-methanol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production follows cGMP guidelines where applicable, and each batch is accompanied by a comprehensive Certificate of Analysis (COA). Our standard purity specification exceeds 97% (by HPLC), ensuring consistency and reliability for your synthetic processes. Certificates of Analysis detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.