Description

3-Bromo-6-Fluoro-2-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethyl group, makes it an indispensable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the halogenated pyridine core enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Fluorinated Compound Libraries: Essential for medicinal chemistry programs focused on creating fluorinated compound libraries to optimize drug metabolism and binding affinity.
• Chemical Research & Development: A versatile scaffold for exploring new chemical spaces and reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Bromo-6-Fluoro-2-(Trifluoromethyl)Pyridine
CAS No.	1227502-92-2
Molecular Formula	C7H2BrF4N
Molecular Weight	243.99 g/mol
Synonyms	2-(Trifluoromethyl)-3-bromo-6-fluoropyridine; 3-Bromo-6-fluoro-2-trifluoromethylpyridine; 6-Fluoro-3-bromo-2-(trifluoromethyl)pyridine; Pyridine, 3-bromo-6-fluoro-2-(trifluoromethyl)-; 1227502-92-2
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoro-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.