Description

2,3-Difluoropyridine-4-Carboxaldehyde is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and an aldehyde functional group, enabling precise molecular modifications for creating high-value compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require sophisticated fluorinated scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides where the difluoropyridine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for synthesizing advanced polymers, liquid crystals, and electronic materials that benefit from fluorination.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities.

Basic Information

Product Name	2,3-Difluoropyridine-4-Carboxaldehyde
CAS No.	1227502-65-9
Molecular Formula	C6H3F2NO
Molecular Weight	143.09 g/mol
Synonyms	4-Formyl-2,3-difluoropyridine; 2,3-Difluoro-4-pyridinecarboxaldehyde; 2,3-Difluoropyridine-4-carbaldehyde; 2,3-Difluoroisonicotinaldehyde; 4-Aldehyde-2,3-difluoropyridine; 2,3-Difluoro-4-formylpyridine; Pyridine-4-carboxaldehyde, 2,3-difluoro-
EINECS	Contact for details

Quality Control

Our 2,3-Difluoropyridine-4-Carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This compound is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.