Description

2-(Bromomethyl)-3-Chloro-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring bromomethyl, chloro, and trifluoromethyl substituents, makes it an exceptionally versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its electron-deficient pyridine core and halogen handles.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Bromomethyl)-3-Chloro-5-(Trifluoromethyl)Pyridine
CAS No.	1227502-50-2
Molecular Formula	C7H4BrClF3N
Molecular Weight	274.47 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)-2-(bromomethyl)pyridine; 2-(Bromomethyl)-3-chloro-5-(trifluoromethyl)pyridine; 3-Chloro-2-(bromomethyl)-5-(trifluoromethyl)pyridine; Pyridine, 2-(bromomethyl)-3-chloro-5-(trifluoromethyl)-; 1227502-50-2; BCTP Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3-Chloro-5-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and MS is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.