Description

5-Fluoro-6-(Hydroxymethyl)Pyridin-2(1H)-One is a high-value, multi-functional pyridinone derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a fluorine substituent and a hydroxymethyl group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials or advanced polymers.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Fluoro-6-(Hydroxymethyl)Pyridin-2(1H)-One
CAS No.	1227490-33-6
Molecular Formula	C6H6FNO2
Molecular Weight	143.12 g/mol
Synonyms	5-Fluoro-6-(hydroxymethyl)-1,2-dihydropyridin-2-one; 5-Fluoro-6-(hydroxymethyl)-2(1H)-pyridinone; 2(1H)-Pyridinone, 5-fluoro-6-(hydroxymethyl)-; 5-Fluoro-6-(hydroxymethyl)pyridin-2-ol; 6-(Hydroxymethyl)-5-fluoropyridin-2(1H)-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 5-Fluoro-6-(Hydroxymethyl)Pyridin-2(1H)-One is analyzed using advanced techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.