Description

B-[4-(1H-Pyrazol-5-Yl)Phenyl]-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biphenyl or heterobiaryl motifs.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for optimal bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Synthesis: A versatile reagent in palladium-catalyzed cross-coupling reactions to construct complex molecular architectures for various R&D applications.
• Ligand Synthesis: Used to prepare novel bidentate or polydentate ligands for catalysis and metal-organic frameworks (MOFs).
• Life Sciences: Employed in the development of biochemical probes and sensor molecules due to its ability to form reversible complexes with diols.

Basic Information

Product Name	B-[4-(1H-Pyrazol-5-Yl)Phenyl]-Boronic Acid
CAS No.	1226849-25-7
Molecular Formula	C9H9BN2O2
Molecular Weight	187.99 g/mol
Synonyms	4-(1H-Pyrazol-5-yl)benzeneboronic acid; [4-(1H-Pyrazol-5-yl)phenyl]boronic acid; 5-(4-Boronophenyl)-1H-pyrazole; B-(4-(1H-Pyrazol-5-yl)phenyl)boronic acid; 4-(1H-Pyrazol-5-yl)phenylboronic acid; 4-(1H-Pyrazol-5-yl)benzeneboronic acid pinacol ester (protected form); 5-(4-Boronophenyl)pyrazole
EINECS	Contact for details

Quality Control

Our B-[4-(1H-Pyrazol-5-Yl)Phenyl]-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.