Description

Thiazovivin is a potent and selective small molecule inhibitor of ROCK (Rho-associated protein kinase) and a key reagent in stem cell research. This compound is critical for enhancing the survival and pluripotency of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) during single-cell passaging. Researchers and biopharmaceutical developers in the fields of regenerative medicine, drug discovery, and developmental biology rely on high-purity Thiazovivin CAS NO 1226056-71-8 to improve cell culture efficiency and experimental reproducibility.

Application

• Enhancement of survival rates for human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) in culture.
• Critical component in protocols for the single-cell passaging of pluripotent stem cells.
• Research tool for studying the ROCK signaling pathway and its role in cell adhesion, motility, and apoptosis.
• Used in organoid development and 3D cell culture systems to maintain cell viability.
• Facilitates high-efficiency cell reprogramming and gene editing workflows in stem cell laboratories.
• Applied in toxicology and drug screening assays utilizing stem cell-derived models.

Basic Information

Product Name	Thiazovivin
CAS No.	1226056-71-8
Molecular Formula	C₁₆H₁₈N₄OS
Molecular Weight	314.41 g/mol
Synonyms	Thiazovivin; N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; 1,3-Thiazole-4-carboxamide, N-benzyl-2-(4-pyrimidinylamino)-; BML-260; ROCK Inhibitor IV; Stemolecule™ Thiazovivin
EINECS	Contact for details

Quality Control

Our Thiazovivin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for sensitive stem cell research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Solubility	Soluble in DMSO, DMF; Slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.