Description

3-Amino-5-Fluoropicolinic Acid, also known as 3-Amino-2-carboxy-5-fluoropyridine, is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid group on a fluorinated pyridine ring, makes it an indispensable intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in metal-organic catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for biochemical assays and diagnostic applications.

Basic Information

Product Name	3-Amino-5-Fluoropicolinic Acid
CAS No.	1225225-14-8
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	3-Amino-2-carboxy-5-fluoropyridine; 5-Fluoro-3-aminopicolinic Acid; 2-Pyridinecarboxylic acid, 3-amino-5-fluoro-; 3-Amino-5-fluoropyridine-2-carboxylic acid; 5-Fluoro-3-aminopyridine-2-carboxylic acid; 3-Amino-5-fluoro-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Fluoropicolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.