Description

(8R,9S,10R,13S,14S,17S)-16,16,17-Trideuterio-17-Hydroxy-10,13-Dimethyl-6,7,8,9,11,12,14,15-Octahydrocyclopenta[A]Phenanthren-3-One is a high-purity, deuterium-labeled steroid derivative, specifically designed for advanced research and analytical applications. This compound is critical for use as an internal standard in mass spectrometry, enabling precise quantification and reducing matrix effects in complex biological samples. It is essential for pharmaceutical R&D, clinical research, and forensic toxicology laboratories focused on steroid hormone analysis, metabolism studies, and drug development.

Application

• Internal Standard for LC-MS/MS: Primary application for the accurate quantification of endogenous steroids and related pharmaceutical compounds in biological matrices (plasma, serum, urine).
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies, metabolism identification (MetID), and bioanalytical method development.
• Clinical Diagnostics & Endocrinology: Enables precise measurement of steroid hormone levels for diagnostic testing and monitoring of endocrine disorders.
• Forensic & Anti-Doping Analysis: Critical for the detection and confirmation of anabolic steroids and other prohibited substances in forensic and sports doping control.
• Isotope Dilution Mass Spectrometry (IDMS): Serves as a stable isotope-labeled analog to achieve high accuracy and precision in reference measurement procedures.
• Biochemical Research: A tool for studying steroid biosynthesis pathways, enzyme activity, and receptor binding assays in vitro.

Basic Information

Product Name	(8R,9S,10R,13S,14S,17S)-16,16,17-Trideuterio-17-Hydroxy-10,13-Dimethyl-6,7,8,9,11,12,14,15-Octahydrocyclopenta[A]Phenanthren-3-One
CAS No.	1224710-35-3
Molecular Formula	C19H25D3O2
Molecular Weight	291.44 g/mol
Synonyms	16,16,17-Trideuterio-17β-Hydroxyandrost-4-en-3-one; Deuterium-labeled Testosterone (d3); 17β-Hydroxy-4-androsten-3-one-16,16,17-d3; Androst-4-en-17β-ol-3-one-16,16,17-d3; Testosterone-16,16,17-d3; [16,16,17-2H3]-Testosterone; d3-Testosterone; Isotopically Labeled Testosterone Internal Standard
EINECS	Contact for details

Quality Control

Every batch of our deuterium-labeled steroid is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity suitable for sensitive analytical applications. Comprehensive testing includes identity confirmation by NMR and MS, assay by HPLC, and determination of isotopic enrichment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. Our quality commitment aligns with the standards expected for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.