Description

Torin 1 is a potent and selective small-molecule inhibitor of the mammalian target of rapamycin (mTOR), specifically targeting the mTORC1 complex. This compound is a critical research tool for studying cellular signaling pathways related to growth, proliferation, and autophagy. It is essential for researchers and developers in the fields of oncology, metabolic disease research, and aging studies who require high-purity biochemical probes for target validation and mechanism-of-action studies.

Application

• Biomedical Research: A key reagent for investigating the mTOR signaling pathway, autophagy, and cell growth regulation in vitro and in vivo.
• Oncology Research: Used to study the role of mTOR in cancer cell proliferation and as a reference compound for developing novel anti-cancer therapeutics.
• Drug Discovery & Development: Serves as a pharmacological tool for target validation, high-throughput screening, and preclinical studies in pharmaceutical R&D.
• Academic Research: Employed in university and institutional labs for fundamental research into metabolism, aging, and neurodegenerative diseases.
• Biochemical Assay Development: Used as a standard and control in developing and validating assays for mTOR kinase activity.

Basic Information

Product Name	Torin 1
CAS No.	1222998-36-8
Molecular Formula	C₃₀H₂₈N₆O₄
Molecular Weight	536.59 g/mol
Synonyms	Torin1; 2-(4-Ethoxyphenyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidine-6-carboxamide; mTOR Kinase Inhibitor Torin 1; ATP-competitive mTOR Inhibitor Torin 1; 4-[4-(1,3-Benzothiazol-2-yl)morpholin-2-yl]phenyl 4-(2-oxo-2-phenylethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our Torin 1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade biochemicals, supporting reproducible and reliable scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.