Description

Tppu is a high-purity, small molecule chemical compound with the CAS registry number 1222780-33-7. This compound is valued for its role as a potent and selective inhibitor of soluble epoxide hydrolase (sEH), a key enzyme involved in the metabolism of anti-inflammatory epoxy fatty acids. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of novel therapeutics for inflammation, pain, and cardiovascular diseases. Our supply ensures consistent quality and reliable availability for critical research and development applications.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and development of sEH inhibitor-based drugs.
• Biochemical Assays: Used as a selective tool compound in enzymatic and cellular assays to study the sEH pathway and its physiological effects.
• Preclinical Studies: Employed in animal models to investigate the therapeutic potential of sEH inhibition for conditions like hypertension, neuropathic pain, and renal disease.
• Fine Chemical Synthesis: Serves as a key building block or intermediate for the synthesis of more complex molecules targeting the sEH enzyme.
• Academic Research: Utilized in university and institutional labs for fundamental research into eicosanoid biology and inflammatory pathways.

Basic Information

Product Name	Tppu
CAS No.	1222780-33-7
Molecular Formula	C21H20F3N3O3
Molecular Weight	419.40 g/mol
Synonyms	1-(1,1,1-Trifluoropropan-2-yl)-3-[[4-[4-(trifluoromethoxy)phenoxy]phenyl]methyl]urea; TPPU; sEH Inhibitor TPPU; Soluble Epoxide Hydrolase Inhibitor TPPU; UC1728; N-[4-[4-(Trifluoromethoxy)phenoxy]benzyl]-N'-(1,1,1-trifluoropropan-2-yl)urea
EINECS	Contact for details

Quality Control

Our Tppu (CAS 1222780-33-7) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.