Description

2-Acetamido-3-o-Acetyl-4,6-o-Benzylidene-n-(tert-Butoxycarbonyl)-1,2,5-Trideoxy-1,5-Imino-D-Glucitol is a sophisticated, multi-protected iminosugar derivative that serves as a critical chiral building block and advanced intermediate in organic synthesis. Its value lies in its complex, selectively protected structure, which is designed for precise manipulation in the synthesis of biologically active compounds, particularly glycosidase inhibitors and complex carbohydrates. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, where it is used to develop novel therapeutics and probe biochemical pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel glycosidase inhibitors and other therapeutic agents.
• Carbohydrate Chemistry Research: Used as a protected precursor in the synthesis of complex oligosaccharides, glycomimetics, and neoglycoconjugates.
• Biochemical Probe Development: Serves as a tool compound for studying enzyme mechanisms, particularly those involving glycosidases and glycosyltransferases.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates targeting carbohydrate-processing enzymes.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities, research institutes, and contract research organizations (CROs).
• Process Chemistry: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs) that require this specific stereochemistry and functionalization.

Basic Information

Product Name	2-Acetamido-3-o-Acetyl-4,6-o-Benzylidene-n-(tert-Butoxycarbonyl)-1,2,5-Trideoxy-1,5-Imino-D-Glucitol
CAS No.	1221795-92-1
Molecular Formula	C24H32N2O8
Molecular Weight	476.52 g/mol
Synonyms	1,2,5-Trideoxy-1,5-imino-2-acetamido-3-O-acetyl-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-D-glucitol; N-Boc-2-acetamido-3-O-acetyl-4,6-O-benzylidene-1,2,5-trideoxy-1,5-imino-D-glucitol; 1,5-Dideoxy-1,5-imino-D-glucitol derivative; Protected D-Glucitol Iminosugar; Advanced Iminosugar Intermediate; CAS 1221795-92-1
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management protocols to ensure consistency and purity for sensitive research and development applications. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.